Abstract: Orobanche spp. can produce a large number of small seeds, which are easily spread by agricultural implements or animals. It has caused severe harm to host plants before emerging to ground. Controlling root parasitic weed Orobanche becomes a worldwide problem. This paper introduced life cycle of Orobanche, harm status and control measures. It highlighted the ecological and economic benefits of biological control. Based on “trap crop” and “catch crop” methods for stimulating Orobanche seeds germination, a new way of eliminating the seed bank within the infested soil for the weeds “suicidal germination” was pointed out. A novel sustaining way for controlling Orobanche weeds was also described.