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Chinese Journal of Biological Control ›› 2021, Vol. 37 ›› Issue (6): 1313-1324.DOI: 10.16409/j.cnki.2095-039x.2021.07.024

• TECHNICAL REVIEWS • Previous Articles    

Progress and Prospects of Insect Sex Determination Mechanism

PENG Wei, ZHAI Zongzhao   

  1. Key Laboratory of Protein Chemistry and Developmental Biology of Fish of Ministry of Education/State Key Laboratory of Developmental Biology of Freshwater Fish/Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation/Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Hunan Normal University, Changsha 410081, China
  • Received:2020-10-14 Published:2021-12-15

Abstract: Insects have evolved a bewildering diversity of regulatory mechanisms to determine the sexes. Sex differentiation is determined by different genes and regulatory mechanisms in different insects, and even the same species with different strains show variability in the mechanisms of sex determination. Understanding the molecular regulation mechanisms of insect sex determination is not only beneficial to reveal the generation and evolution of sex, but also provide theoretical and practical foundation for the genetic operation of insects. In this paper, we review the primary signals of sex determination and its regulation mechanisms in different insects, and introduce the research status quo of the sex determination cascade bottom gene doublesex and key genes transformer and transformer-2 in insect sex determination, in order to provide new ideas and supports in sterile insect technique by targeting the insect sex determination.

Key words: sex determination, primary signal, cascade genes, regulation mechanism, sterile insect technique

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