Research and Application of Nanoparticle-mediated RNAi Technology in Pest Control

doi:10.16409/j.cnki.2095-039x.2021.01.020

Abstract

Abstract: Each year, the epidemic and outbreak of major diseases and pests will have a major impact on agriculture, resulting in serious economic losses, with the application of chemical reagents its resistance has gradually increased, therefore, it is of great significance to explore new green, safe and efficient pest control technology. RNAi, as a tool to study gene function, has shown great potential in developing new pest control strategies. However, the efficiency of RNAi is limited by the degradation effect of nuclease. In order to improve the effective delivery of dsRNA, nanoparticle-mediated technology was developed and widely used in pest control. At the same time, the efficient synthesis of targeted insect dsRNA based on engineered bacteria provides feasibility and technical support for field promotion. This paper mainly summarized the research and application of RNAi technology and nanoparticle-mediated technology in pest control.

Key words: nanoparticle-mediated, dsRNA preparations, RNA interference, pest control

CLC Number:

S476

WANG Xiaodi, JI Shunxia, SHEN Xiaona, LIU Wanxue, WAN Fanghao, ZHANG Guifen, Lü Zhichuang. Research and Application of Nanoparticle-mediated RNAi Technology in Pest Control[J]. Chinese Journal of Biological Control, 2021, 37(6): 1298-1312.

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