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Chinese Journal of Biological Control ›› 2022, Vol. 38 ›› Issue (3): 700-715.DOI: 10.16409/j.cnki.2095-039x.2021.11.015

• TECHNICAL REVIEWS • Previous Articles    

The Development of Biological Pesticides Based on RNA Interference

GAO Liwen, CHEN Shiguo, ZHANG Yu, QIANG Sheng   

  1. College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China
  • Received:2021-04-06 Published:2022-06-20

Abstract: RNA interference, also known as post transcriptional gene silencing, is an emerging new genetic engineering technique that can effectively silence or inhibits the expression of target genes. Biopesticides based on RNA interference are considered as a revolutionary technique in the field of plant protection in the future, which will completely change the ideas and strategies of controlling agricultural diseases, insects, weeds and other pests. Here, the basic principle and development process of RNA interference were briefly reviewed. The current status of research and application of RNAi biopesticides was summarized. The opportunities and challenges to develop RNAi biopesticides as well as its development prospect were deeply analyzed. This review serves to provide some valuable references for the development of RNAi biopesticides in China.

Key words: RNA interference, RNA pesticides, crop protection

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