Abstract: MoHrip1 and MoHrip2 are secretory effector proteins extracted from Magnaporthe oryzae. Previous experiments showed MoHrip1 and MoHrip2 could improve rice resistance to blast disease, and induce expression of disease-related genes. In this experiment, expression vectors were constructed to express MoHrip1 and MoHrip2 proteins, and then proteins were purified to a high concentration. The results showed that MoHrip1 and MoHrip2 could obviously control rice bacterial blight at different concentrations. Lesion length and lesion diffusion rate of the treatments were significantly lower than those of control. The efficiencies at 1, 5, 10, 15, 30 μmol/L MoHrip1 to control bacterial blight were 70.80%, 72.56%, 72.56%, 80.54%, 92.92%, respectively. The differences between the control efficiency at 30 μmol/L and those at 1, 5, 10 μmol/L MoHrip1 were significant, while the differences among those at 1, 5, 10, 15 μmol/L MoHrip1 were not significant. The control efficiencies at 1, 5, 10, 15, 30 μmol/L MoHrip2 to suppress bacterial blight were 69.99%, 70.60%, 71.54%, 70.99% and 72.55%, respectively. The differences among the control efficiencies at different concentrations of MoHrip2 were not significant, either. The experiments showed that the protein elicitor MoHrip1 and MoHrip2 could significantly induce rice resistance to bacterial blight, showing an application prospects in the future.