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Chinese Journal of Biological Control ›› 2022, Vol. 38 ›› Issue (5): 1117-1124.DOI: 10.16409/j.cnki.2095-039x.2022.09.008


Transgenic Maize with cry1Ac and epsps Gene Had no Effects on the Growth Performance and Reproduction of Zebrafish (Danio rerio)

ZHANG Li1, ZHU Xuexia2, SHEN Wenjing1, LIU Biao1   

  1. 1. Key Laboratory on Biodiversity and Biosafety of Environmental Protection/Nanjing Institute of Environmental Science, Ministry of Ecology and Environment, Nanjing 210042, China;
    2. College of Oceanography, Hohai University, Nanjing 210098, China
  • Received:2022-07-15 Published:2022-10-20

Abstract: A 56-day zebrafish Danio rerio feeding study was conducted with diets containing 22% genetically modified (GM) maize meal to evaluate potential feed safety risk compared with non-transgenic,near-isoline soybean and conventional comparators.Zebrafish growth performance,egg reproduction,as well as the potentiality of transfer of transgenic protein from GM feed to zebrafish tissues (muscle,liver,and intestines) were measured during the feeding trial.Results showed that the body length,weight,egg reproduction for zebrafish fed the DBN9936 corn were not significantly different from the respective values for zebrafish fed diets formulated with control maize grain,and the transgenic Cry1Ab and EPSPS proteins were undetectable by Western blot in the tissues samples of zebrafish fed a diet containing GM maize,indicated that transgenic protein are not transferred to zebrafish tissues.According to the obtained results,there was no negative effect of DBN9936 transgenic maize on zebrafish body length,weight,or egg reproduction,suggested that DBN9936 transgenic maize is as safe and nutritious source of feed as its no transgenic control.

Key words: transgenic maize, zebrafish, growth performance, reproduction, foreign protein residues in tissues

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