Research and Application Development History and Prospects of Bacillus thuringiensis in China

doi:10.16409/j.cnki.2095-039x.2026.05.002

Abstract

Abstract: As a core microbial resource for agricultural biological control, Bacillus thuringiensis (Bt) represents an important epitome of the development of biological control discipline in China. This paper systematically reviews the development history of Bt research and application in China, from technological catching-up to independent innovation, and then to the forefront of the international community. It systematically elaborates the core achievements of China in the fields of Bt insecticidal gene mining, insecticidal mechanism analysis, insecticide development, and application of transgenic insect-resistant crops. Meanwhile, it analyzes the current challenges faced by Bt research, such as escalating pest resistance, insufficient field stability of formulations, and single resource utilization mode. Furthermore, combined with cutting-edge technologies including artificial intelligence and synthetic biology, this paper prospects the future research directions from the aspects of targeted design of novel insecticidal proteins, industrial upgrading of formulations, resistance monitoring and management, and expansion of cross-field applications, so as to provide theoretical support and practical reference for the improvement of agricultural green prevention and control system and the guarantee of food security in China.

Key words: biological control, Bacillus thuringiensis, development history, prospects

CLC Number:

S476.1

SHU Changlong, PENG Donghai Peng, CAO Beibei, XIE Jiajian, ZHANG Jie. Research and Application Development History and Prospects of Bacillus thuringiensis in China[J]. Chinese Journal of Biological Control, 2026, 42(2): 278-291.

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